| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GMEB1 |
| Specificity: |
This antibody reacts specifically with GMEB1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GMEB1 |
| Gene ID: |
10691 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Due to alternative splicing events, GMEB-1 also interacts with initiator procaspases and, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, GMEB-1 functions alone as a trans-acting factor that, GMEB-1 is expressed as two isoforms, In addition, Localized to both the cytoplasm and the nucleus, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, can inhibit caspase-induced apoptosis, increases intracellular sensitivity to glucocorticoid concentrations, once associated with GMEB-2, plays a key role in parvovirus DNA replication, via this interaction, GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
P96PIF PIF96 |
| Also known as: |
GMEB1 Polyclonal Antibody |
| Other name: |
Anti-GMEB1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GMEB1 |
| Short name: |
Anti-GMEB1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GMEB1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4370 |
| Gene: |
GMEB1 |
More about : GMEB1 |
| Long gene name: |
glucocorticoid modulatory element binding protein 1 |
| Locus: |
1p35, 3 |
| Discovery year: |
1999-07-07 |
| GenBank acession: |
AF099013 |
| Entrez gene record: |
10691 |
| Pubmed identfication: |
10386584 10523663 |
| RefSeq identity: |
NM_006582 |
| Havana BLAST/BLAT: |
OTTHUMG00000003647 |