| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GFAP Ser38 |
| Specificity: |
This antibody reacts specifically with GFAP (Ser38) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser38 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human GFAP around the phosphorylation site of Ser38 |
| Gene ID: |
2670 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GFAP is also found in the lens epithelium, In addition, In addition many types of brain tumor, It is heavily, Kupffer cells of the liver, and in non myelinating Schwann cells in peripheral nerves, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, heavily express GFAP, in satellite cells in peripheral ganglia, in some cells in salivary tumors and has been reported in erythrocytes, neural stem cells frequently strongly express GFAP, presumably derived from astrocytic cells, to GFAP are therefore very useful as markers of astrocytic cells, Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ45472 |
| Also known as: |
GFAP (Ser38) Polyclonal Antibody |
| Other name: |
Anti-GFAP (Ser38) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GFAP (Ser38) |
| Short name: |
Anti-GFAP (Ser38) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GFAP (Ser38) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4235 |
| Gene: |
GFAP |
More about : GFAP |
| Long gene name: |
glial fibrillary acidic protein |
| Synonyms name: |
intermediate filament protein |
| Locus: |
17q21, 31 |
| Discovery year: |
1989-12-07 |
| GenBank acession: |
S40719 |
| Entrez gene record: |
2670 |
| Pubmed identfication: |
9693047 |
| RefSeq identity: |
NM_002055 |
| Classification: |
Intermediate filaments Type III |
| Havana BLAST/BLAT: |
OTTHUMG00000179866 |