| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GSDML/Gasdermin like |
| Specificity: |
This antibody reacts specifically with GSDML/Gasdermin like |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GSDML/Gasdermin like |
| Gene ID: |
55876 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GSDML is a widely expressed protein found in both cancerous and non-cancerous tissues localizing to the cytoplasm and in secretory vesicles, In addition, Members of the GSDMDC family are involved in a wide variety of cellular processes, The gene encoding GSDML is thought to have been generated by a duplication event of the GSDM1 gene which encodes gasdermin, and have been associated with the development and progression of cancer, differentiation and apoptosis, extracellular matrix production, including cell-cycle control, various isoforms exist for GSDML, GSDML is a member of the GSDMDC (gasdermin-domain containing) family of proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PRO2521 |
| Also known as: |
GSDML/Gasdermin like Polyclonal Antibody |
| Other name: |
Anti-GSDML/Gasdermin like Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GSDML/Gasdermin like |
| Short name: |
Anti-GSDML/Gasdermin like (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GSDML/Gasdermin like (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23690 |
| Gene: |
GSDMB |
More about : GSDMB |
| Long gene name: |
gasdermin B |
| Synonyms gene: |
GSDML |
| Synonyms gene name: |
gasdermin-like |
| Locus: |
17q21, 1 |
| Discovery year: |
2003-12-09 |
| GenBank acession: |
AF119884 |
| Entrez gene record: |
55876 |
| Pubmed identfication: |
12883658 15010812 17350798 |
| RefSeq identity: |
NM_018530 |
| Havana BLAST/BLAT: |
OTTHUMG00000133248 |