| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
gamma Adaptin |
| Specificity: |
This antibody reacts specifically with gamma Adaptin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human gamma Adaptin |
| Gene ID: |
164 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AP180 (also designated AP-3 or F1-20) is a synapse-specific clathrin assembly protein, The AP-1 and AP-2 adapter protein complexes consist of clathrin binding adaptin proteins (g and b1 for AP-1, The a and b adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length, The protein CALM (clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in clathrin assembly, Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17, a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues, Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with clathrin associated protein complexes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
VEAR KIAA1080 |
| Also known as: |
gamma Adaptin Polyclonal Antibody |
| Other name: |
Anti-gamma Adaptin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
gamma Adaptin |
| Short name: |
Anti-gamma Adaptin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-g Adaptin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
16064 |
| Gene: |
GGA2 |
More about : GGA2 |
| Long gene name: |
ARF binding protein 2 , gamma adaptin ear containing, golgi associated |
| Synonyms gene name: |
ARF binding protein 2 , gamma adaptin ear containing, golgi-associated |
| Locus: |
16p12, 2 |
| Discovery year: |
2001-12-19 |
| GenBank acession: |
AF190863 |
| Entrez gene record: |
23062 |
| Pubmed identfication: |
10747088 10749927 |
| Classification: |
ARF binding proteins , Golgi associated, gamma adaptin ear containing |
| Havana BLAST/BLAT: |
OTTHUMG00000096957 |