| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
G6PC3 |
| Specificity: |
This antibody reacts specifically with G6PC3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human G6PC3 |
| Gene ID: |
92579 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
3), Due to its necessary involvement in normal glucose metabolism, G6Pase localizes to the endoplasmic reticulum, G6Pase-Alpha, G6Pase-Beta, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs), Inhibited by vanadate, UGRP or G6PC3 (glucose 6 phosphatase, a second form, also known as SCN4, and intestine are the only tissues that express the first identified isoform, and while liver, catalytic, contributes to blood glucose homeostasis in a wider range of tissues, designated G6Pase-Beta, is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway, is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis, kidney, Glucose-6-phosphatase (G6Pase) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
UGRP |
| Also known as: |
G6PC3 Polyclonal Antibody |
| Other name: |
Anti-G6PC3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
G6PC3 |
| Short name: |
Anti-G6PC3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-G6PC3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
24861 |
| Gene: |
G6PC3 |
More about : G6PC3 |
| Long gene name: |
glucose-6-phosphatase catalytic subunit 3 |
| Synonyms gene name: |
3 , catalytic, glucose 6 phosphatase |
| Locus: |
17q21, 31 |
| Discovery year: |
2004-03-29 |
| GenBank acession: |
BC021574 |
| Entrez gene record: |
92579 |
| Pubmed identfication: |
12370122 12965222 |
| RefSeq identity: |
NM_138387 |
| Classification: |
Glucose 6-phosphatases, catalytic |
| Havana BLAST/BLAT: |
OTTHUMG00000181805 |
| Locus Specific Databases: |
LRG_182 |