| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FN3K |
| Specificity: |
This antibody reacts specifically with FN3K |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FN3K |
| Gene ID: |
64122 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
FN3K is a monomer that is ubiquitously expressed in mammalian tissue and phosphorylates both low molecular mass and protein-bound fructosamines which are formed as a result of glycation of glucose with primary amines, FN3K protects proteins from the harmful effects of nonenzymatic glycation, FN3KRP (fructosamine-3-kinase-related protein) is a 309 amino acid protein that is expressed in erythrocytes, FN3KRP functions to phosphorylate psicoamines and ribulosamines on the third carbon of their sugar moiety, Fructosamine 3-kinase (FN3K), a 309-amino acid enzyme initially identified in erythrocytes, and may also be involved in peptide repair and cell metabolism, bone marrow, brain and kidney and belongs to the fructosamine kinase family, catalyzes the ATP-dependent phosphorylation of the third carbon on both D- and L-fructosamines, including those present on proteins, leading to their destabilization and eventually, spleen, spontaneously react with glucose to make fructosamines in a reaction termed glycation, their removal from the protein, thereby leading to the deglycation of the target amines, Amines |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
FN3K Polyclonal Antibody |
| Other name: |
Anti-FN3K Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FN3K |
| Short name: |
Anti-FN3K (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FN3K (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
24822 |
| Gene: |
FN3K |
More about : FN3K |
| Long gene name: |
fructosamine 3 kinase |
| Locus: |
17q25, 3 |
| Discovery year: |
2004-11-29 |
| GenBank acession: |
AJ404615 |
| Entrez gene record: |
64122 |
| Pubmed identfication: |
11522682 14641062 |
| RefSeq identity: |
NM_022158 |
| Havana BLAST/BLAT: |
OTTHUMG00000177847 |