| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FGFR3 Tyr724 |
| Specificity: |
This antibody reacts specifically with FGFR3 (Tyr724) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr724 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human FGFR3 around the phosphorylation site of Tyr724 |
| Gene ID: |
2261 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants encoding the same protein have been described, In other tissues, Mutations in this gene have been associated with early onset obesity, These include several distinct melanotropins, adrenal insufficiency, adrenocorticotrophin, all cleavage sites may be used, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides, and epithelium, and immune modulation, and lipotropin beta are the major end products, and red hair pigmentation, essential for normal steroidogenesis and the maintenance of normal adrenal weight, giving rise to peptides with roles in pain and energy homeostasis, including the hypothalamus, lipotropins, melanocyte stimulation, placenta, The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CEK2 JTK4 CD333 |
| Also known as: |
FGFR3 (Tyr724) Polyclonal Antibody |
| Other name: |
Anti-FGFR3 (Tyr724) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FGFR3 (Tyr724) |
| Short name: |
Anti-FGFR3 (Tyr724) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FGFR3 (Tyr724) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3690 |
| Gene: |
FGFR3 |
More about : FGFR3 |
| Long gene name: |
fibroblast growth factor receptor 3 |
| Synonyms gene: |
ACH |
| Synonyms gene name: |
achondroplasia, thanatophoric dwarfism |
| Locus: |
4p16, 3 |
| Discovery year: |
1991-06-07 |
| GenBank acession: |
M64347 |
| Entrez gene record: |
2261 |
| Pubmed identfication: |
1847508 |
| RefSeq identity: |
NM_000142 |
| Classification: |
I-set domain containing CD molecules Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000121148 |
| Locus Specific Databases: |
LRG_1021 |