| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FCGBP |
| Specificity: |
This antibody reacts specifically with FCGBP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FCGBP |
| Gene ID: |
8857 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
FCGBP is a 5, Fc receptors are present on lymphoid and myeloid derivatives, It is predominantly expressed in placenta and colon epithelium as well as in thyroid and serum, Patients with various autoimmune diseases seemingly have higher levels of FCGBP protein present in their serum, The Fc Î, antibody production in B cells through T cell antigen presentation, by removing Ig-coated antigen complexes from circulation, cytotoxicity and the release of cytokines and reactive oxygen species, such as microorganisms and pathogens, where they mediate endocytosis of Ig-antigen complexes, ³, -binding protein (FCGBP) interacts with the Fc portion of IgG and MUC2 to mediate the maintenance of the mucosal structure, 405 amino acid protein that contains twelve TIL (trypsin inhibitory-like) domains and thirteen VWFD domains, Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FC(GAMMA)BP |
| Also known as: |
FCGBP Polyclonal Antibody |
| Other name: |
Anti-FCGBP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FCGBP |
| Short name: |
Anti-FCGBP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FCGBP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13572 |
| Gene: |
FCGBP |
More about : FCGBP |
| Long gene name: |
Fc fragment of IgG binding protein |
| Synonyms name: |
IgG Fc binding protein Human Fc gamma BP |
| Locus: |
19q13, 2 |
| Discovery year: |
2000-09-26 |
| GenBank acession: |
D84239 |
| Entrez gene record: |
8857 |
| Pubmed identfication: |
9182547 |
| RefSeq identity: |
NM_003890 |
| Havana BLAST/BLAT: |
OTTHUMG00000182580 |