| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FGR/SRC2 |
| Specificity: |
This antibody reacts specifically with FGR/SRC2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FGR/SRC2 |
| Gene ID: |
2268 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, Fgr, Frk, Fyn, Hck, Lck and Blk, Lyn, Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human, Src-family ki-nases contain an amino-terminal cell membrane anchor followed by an SH3 domain and an SH2 domain, Src-family kinases, Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, The Src family, The human c-Fgr gene encodes a 529 amino acid protein, Yes, also designated avian sarcoma virus or ASV, c-Fgr is a human non-receptor tyrosine kinase family member that was discovered by using a probe toward the v-Fgr portion of the cell-derived domain of Gardner-Rasheed feline sarcoma virus, cytoskeletal organization and membrane trafficking, differentiation, including Src, including proliferation, is composed of nine members in vertebrates, motility and adhesion, respectively, which are involved in modular association and activation, which are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis, which has common structural motifs, Src is the human homolog of the v-Src gene of the rous sarcoma virus |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
c-fgr p55c-fgr |
| Also known as: |
FGR/SRC2 Polyclonal Antibody |
| Other name: |
Anti-FGR/SRC2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FGR/SRC2 |
| Short name: |
Anti-FGR/SRC2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FGR/SRC2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3697 |
| Gene: |
FGR |
More about : FGR |
| Long gene name: |
FGR proto-oncogene, Src family tyrosine kinase |
| Synonyms gene: |
SRC2 |
| Synonyms gene name: |
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog feline Gardner-Rasheed sarcoma viral oncogene homolog |
| Locus: |
1p35, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC064382 |
| Entrez gene record: |
2268 |
| Pubmed identfication: |
3922831 |
| RefSeq identity: |
NM_005248 |
| Classification: |
SH2 domain containing Src family tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000003516 |