| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FBP17 |
| Specificity: |
This antibody reacts specifically with FBP17 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FBP17 |
| Gene ID: |
23048 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, Expressed at high levels in respiratory, FNBP1, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, and contains one FCH domain, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, cytoskeleton, enhances Actin polymerization and promotes membrane invagination and the formation of tubules, including the cytoplasm, lysosome and the cell cortex, one REM repeat and one SH3 domain, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis, reproductive and urinary systems, suggesting a role for defective FNBP1 in carcinogenesis, which exists as four alternatively spliced isoforms, FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FBP17 KIAA0554 |
| Also known as: |
FBP17 Polyclonal Antibody |
| Other name: |
Anti-FBP17 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FBP17 |
| Short name: |
Anti-FBP17 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FBP17 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17069 |
| Gene: |
FNBP1 |
More about : FNBP1 |
| Long gene name: |
formin binding protein 1 |
| Locus: |
9q34, 11 |
| Discovery year: |
2002-11-25 |
| GenBank acession: |
AB011126 |
| Entrez gene record: |
23048 |
| Pubmed identfication: |
9628581 11438682 |
| Classification: |
F-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020800 |