| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
EFEMP2/Fibulin 4 |
| Specificity: |
This antibody reacts specifically with EFEMP2/Fibulin 4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human EFEMP2/Fibulin 4 |
| Gene ID: |
30008 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in the gene encoding Fibulin-4 are associated with autosomal recessive cutis laxa type I (CL type I), Expressed ubiquitously with highest expression in heart, Fibulin-4, Fibulin-4 is essential for connective tissue development and elastic fiber formation, MBP1 or UPH1 is a 443 amino acid secreted protein that contains six EGF-like calcium-binding domains and belongs to the fibulin family, a connective tissue disorder that is inherited in both an autosomal dominant and an autosomal recessive manner and is characterized by inelastic tissue in all affected areas of the body, also known as EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2), and may also play an important role in vascular patterning and collagen biosynthesis, lung and skin, such as vasculature, Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FBLN4 UPH1 |
| Also known as: |
EFEMP2/Fibulin 4 Polyclonal Antibody |
| Other name: |
Anti-EFEMP2/Fibulin 4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
EFEMP2/Fibulin 4 |
| Short name: |
Anti-EFEMP2/Fibulin 4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-EFEMP2/Fibulin 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3219 |
| Gene: |
EFEMP2 |
More about : EFEMP2 |
| Long gene name: |
EGF containing fibulin like extracellular matrix protein 2 |
| Synonyms gene name: |
EGF-containing fibulin-like extracellular matrix protein 2 |
| Synonyms name: |
fibulin 4 |
| Locus: |
11q13, 1 |
| Discovery year: |
2000-03-01 |
| GenBank acession: |
AF109121 |
| Entrez gene record: |
30008 |
| Pubmed identfication: |
10601734 10982184 |
| RefSeq identity: |
NM_016938 |
| Classification: |
Fibulins |
| Havana BLAST/BLAT: |
OTTHUMG00000166664 |