| Type: |
Primary Antibody |
| Conjugated with: |
Unconjugated |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DUSP5 |
| Specificity: |
This antibody reacts specifically with DUSP5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DUSP5 |
| Gene ID: |
1847 |
| Applications: |
WB |
| Applications with corresponding dilutions: |
WB(1:100-1000) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DSP gene expression is induced by a host of growth factors and/or cellular stresses, DUSP1, DUSP5, DUSP5 is a nuclear phosphoprotein that displays phosphatase activity toward several different substrates, DUSP8, It shows the highest relative activity toward ERK1, MKP-2, MKP-3, MKP-4, MKP-5, MKP-6, MKP-7, MKP-X, PAC1, PIR1 and SKRP1, PYST2, SAPK/JNK and p38, The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, VHY, hVH-3 (B23), hVH-5, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases, Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Synonyms: |
HVH3 |
| Also known as: |
DUSP5 Polyclonal Antibody |
| Other name: |
Anti-DUSP5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DUSP5 |
| Short name: |
Anti-DUSP5 (Polyclonal) |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Alternative name: |
antibody to-DUSP5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3071 |
| Gene: |
DUSP5 |
More about : DUSP5 |
| Long gene name: |
dual specificity phosphatase 5 |
| Locus: |
10q25, 2 |
| Discovery year: |
1994-12-14 |
| GenBank acession: |
U16996 |
| Entrez gene record: |
1847 |
| Pubmed identfication: |
7806236 |
| RefSeq identity: |
NM_004419 |
| Classification: |
MAP kinase phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000019040 |