| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DREF/ZBED1 |
| Specificity: |
This antibody reacts specifically with DREF/ZBED1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DREF/ZBED1 |
| Gene ID: |
9189 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, Expressed ubiquitously at low levels and present at higher levels in heart, ZBED1 binds strongly to the promotor region of Histone H1 (a protein required for the condensation of nucleosomes into higher order structures), ZBED1 contains one BED-type zinc finger and binds specifically to 5'-TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors, ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoding genes, placenta, spleen and skeletal muscle, subsequently activating H1 transcription, thereby playing a role in the cell cycle and in cell proliferation events, ZBED1 is a 694 amino acid protein that localizes specifically to granular structures within the nucleus |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TRAMP KIAA0785 DREF hDREF |
| Also known as: |
DREF/ZBED1 Polyclonal Antibody |
| Other name: |
Anti-DREF/ZBED1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DREF/ZBED1 |
| Short name: |
Anti-DREF/ZBED1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DREF/ZBED1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
447 |
| Gene: |
ZBED1 |
More about : ZBED1 |
| Long gene name: |
zinc finger BED-type containing 1 |
| Synonyms gene: |
ALTE |
| Synonyms gene name: |
Ac-like transposable element |
| Locus: |
Xp22, 33 and Yp11 |
| Discovery year: |
2000-05-11 |
| GenBank acession: |
AB018328 |
| Entrez gene record: |
9189 |
| Pubmed identfication: |
9872452 9887332 23533661 |
| RefSeq identity: |
NM_004729 |
| Classification: |
Zinc fingers BED-type Pseudoautosomal region 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000021069 |
| Locus Specific Databases: |
Mental Retardation database |