| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CSP |
| Specificity: |
This antibody reacts specifically with CSP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CSP |
| Gene ID: |
80331 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
C-terminally truncated isoform, CSP contains a J-domain that binds HSP 70/HSC 70 chaperone ATPases and a membrane-targeting, CSP is involved in the fine tuning of neurotransmission through its interaction with receptor-coupled trimeric GTP binding proteins (G proteins) and N-type Ca2+ channels, CSP2, CSPs may act as molecular chaperones in synapses, Furthermore, Subcellular fractionation of insulinoma cells shows CSP1 in granular fractions, The fractions also contain additional proteins, Two variants of CSP have been described: CSP1, and mediate conformational folding of components of the vesicular exocytotic machinery, and the 31 amino acid, in various mammalian cell lines (including rat brain) CSP1 expression predominates CSP2 expression, palmitoylated cysteine-rich string region, presumably CSP dimers, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic vesicles and modulation of presynaptic transmembrane calcium fluxes in neuroendocrine and endocrine cell types, while the membrane and cytosol fractions contain predominantly CSP2, Cysteine string proteins (CSPs) are synaptic vesicle-associated |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CLN4, CLN4B, CSP, Cysteine string protein, DJC5, DNAJC 5, DNAJC5A, DNJC5_HUMAN, DnaJ Hsp40 homolog subfamily C member 5, DnaJ homolog subfamily C member 5, Dnajc5, NCL, cysteine string protein alpha, CLN 4 |
| Also known as: |
CSP Polyclonal Antibody |
| Other name: |
Anti-CSP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CSP |
| Short name: |
Anti-CSP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CSP (polyclonal) |
| Alternative technique: |
polyclonals |