| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ING1/p33ING1b |
| Specificity: |
This antibody reacts specifically with ING1/p33ING1b |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human inhibitor of growth gene 1 |
| Gene ID: |
3621 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, Reduced expression and rearrangement of this gene have been detected in various cancers, The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway, [provided by RefSeq], This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p33ING1 p33ING1b p24ING1c p33 p47 p47ING1a |
| Also known as: |
ING1/p33ING1b Polyclonal Antibody |
| Other name: |
Anti-ING1/p33ING1b Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ING1/p33ING1b |
| Short name: |
Anti-ING1/p33ING1b (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ING1/p33ING1b (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6062 |
| Gene: |
ING1 |
More about : ING1 |
| Long gene name: |
inhibitor of growth family member 1 |
| Synonyms name: |
inhibitor of growth 1 tumor suppressor ING1 growth inhibitor ING1 growth inhibitory protein ING1 |
| Locus: |
13q34 |
| Discovery year: |
1996-10-26 |
| Entrez gene record: |
3621 |
| Pubmed identfication: |
8944021 9186514 |
| RefSeq identity: |
NM_005537 |
| Classification: |
PHD finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000017346 |