| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BPY2 |
| Specificity: |
This antibody reacts specifically with BPY2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BPY2 |
| Gene ID: |
442867 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BPY2 interacts with MAP-1S, BPY2 protein expression is localized to the nuclei of spermatogonia, BPY2B, BPY2C) reside in the AZFc region, Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development, Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis, The analysis of mutations has provided insight into biochemical pathways required for completion of this process, The basic protein on Y chromosome 2 gene (BPY2, Three copies (paralogs) of the BPY2 gene (BPY2A, also designated VCY2) is located in a frequently deleted azoospermia factor c region, but is absent from elongated spermatids, spermatocytes and round spermatids, suggesting a role for BPY2 within the cytoskeletal network, which shares homology with microtubule-associated proteins (MAPs), Mammalian spermatogenesis is a complex developmental process |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BPY2A VCY2A |
| Also known as: |
BPY2 Polyclonal Antibody |
| Other name: |
Anti-BPY2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BPY2 |
| Short name: |
Anti-BPY2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-BPY2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13508 |
| Gene: |
BPY2 |
More about : BPY2 |
| Long gene name: |
2 , Y-linked, basic charge |
| Synonyms gene: |
VCY2 |
| Synonyms gene name: |
2 , Y-linked, variable charge |
| Locus: |
Yq11, 223 |
| Discovery year: |
2000-09-25 |
| GenBank acession: |
AF000980 |
| Entrez gene record: |
9083 |
| RefSeq identity: |
NM_004678 |
| Havana BLAST/BLAT: |
OTTHUMG00000058899 |