| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BMP8b |
| Specificity: |
This antibody reacts specifically with BMP8b |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BMP8b |
| Gene ID: |
656 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, BMP-8 (also designated OP-2) is thought to be involved in early development, BMPs are involved in the induction of cartilage and bone formation, In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation, Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), as detectable expression has not been found in adult organs, indicating that they each may be able to induce cartilage formation, suggesting that BMP-4 may play a role in activation of the Smad pathway, Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
OP-2 |
| Also known as: |
BMP8b Polyclonal Antibody |
| Other name: |
Anti-BMP8b Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BMP8b |
| Short name: |
Anti-BMP8b (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-bone morphogenetic protein 8b (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1075 |
| Gene: |
BMP8B |
More about : BMP8B |
| Long gene name: |
bone morphogenetic protein 8b |
| Synonyms gene: |
BMP8 |
| Synonyms gene name: |
bone morphogenetic protein 8 (osteogenic protein 2) |
| Synonyms name: |
osteogenic protein 2 |
| Locus: |
1p34, 2 |
| Discovery year: |
1995-11-02 |
| GenBank acession: |
BC023526 |
| Entrez gene record: |
656 |
| Pubmed identfication: |
1460021 9070944 |
| RefSeq identity: |
NM_001720 |
| Classification: |
Endogenous ligands Bone morphogenetic proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000009247 |