| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FGF4 |
| Specificity: |
This antibody reacts specifically with FGF4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FGF4 |
| Gene ID: |
2249 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Co-amplification of both genes was found in various kinds of human tumors, FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway, This gene and FGF3, This gene was identified by its oncogenic transforming activity, [provided by RefSeq], another oncogenic growth factor, are located closely on chromosome 11, cell growth, morphogenesis, tissue repair, tumor growth and invasion, The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
K-FGF HBGF-4 HST HST-1 KFGF |
| Also known as: |
FGF4 Polyclonal Antibody |
| Other name: |
Anti-FGF4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FGF4 |
| Short name: |
Anti-FGF4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-fibroblast growth factor 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, FGF4 and IDBG-62016 and ENSG00000075388 and 2249, Fgf4 and IDBG-212951 and ENSMUSG00000050917 and 14175, HBGF-4 and HST and HST-1 and HSTF1 and K-FGF and KFGF, heparin binding, nuclei, this GO :0001502 and cartilage condensation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005104 and fibroblast growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010463 and mesenchymal cell proliferation and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0060363 and cranial suture morphogenesis and biological process this GO :0060561 and apoptotic process involved in morphogenesis and biological process this GO :0060591 and chondroblast differentiation and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process, this GO :0005104 : fibroblast growth factor receptor binding, this GO :0005104 : fibroblast growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0008201 : heparin binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0008201 : heparin binding, 62944 and IDBG-645032 and ENSBTAG00000012563 and 618474, fibroblast growth factor 4 |
| Identity: |
3682 |
| Gene: |
FGF4 |
More about : FGF4 |
| Long gene name: |
fibroblast growth factor 4 |
| Synonyms gene: |
HSTF1 |
| Synonyms gene name: |
heparin secretory transforming protein 1 |
| Synonyms name: |
human stomach cancer, transforming factor from FGF-related oncogene kaposi sarcoma oncogene transforming protein KS3 |
| Locus: |
11q13, 3 |
| Discovery year: |
1988-04-20 |
| GenBank acession: |
M17446 |
| Entrez gene record: |
2249 |
| Pubmed identfication: |
1611909 |
| RefSeq identity: |
NM_002007 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000167887 |