| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
API5 |
| Specificity: |
This antibody reacts specifically with API5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human API5 |
| Gene ID: |
8539 |
| Swiss Prot: |
Q9BZZ5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also known to efficiently suppress E2F1-induced apoptosis, By binding to ACIN1, Its depletion enhances the cytotoxic action of the chemotherapeutic drugs, Negatively regulates ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation, Antiapoptotic factor that may have a role in protein assembly |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AAC-11 API5L1 AAC11 |
| Also known as: |
API5 Polyclonal Antibody |
| Other name: |
Anti-API5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
API5 |
| Short name: |
Anti-API5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-apoptosis inhibitor 5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AAC-11 and AAC11, API5 and IDBG-40293 and ENSG00000166181 and 8539, API5 and IDBG-636799 and ENSBTAG00000014474 and 538968, Api5 and IDBG-193023 and ENSMUSG00000027193 and 11800, nuclei, poly(A) RNA binding, this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005681 and spliceosomal complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0016020 and membrane and cellular component this GO :0017134 and fibroblast growth factor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :2000270 and negative regulation of fibroblast apoptotic process and biological process, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0017134 : fibroblast growth factor binding and also this GO :0044822 : poly(A) RNA binding, this GO :0005515 : protein binding, this GO :0017134 : fibroblast growth factor binding, this GO :0044822 : poly(A) RNA binding, apoptosis inhibitor 5 |
| Identity: |
594 |
| Gene: |
API5 |
More about : API5 |
| Long gene name: |
apoptosis inhibitor 5 |
| Synonyms name: |
API5-like 1 fibroblast growth factor 2-interacting factor 2 migration-inducing protein MIG8 |
| Locus: |
11p12 |
| Discovery year: |
1998-10-06 |
| GenBank acession: |
U83857 |
| Entrez gene record: |
8539 |
| Pubmed identfication: |
9307294 |
| RefSeq identity: |
NM_006595 |
| Havana BLAST/BLAT: |
OTTHUMG00000166395 |