Anti-AMPK alpha 2 (Ser491), ALEXA Fluor 594

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Catalog number: GENTAUR-58be5ca17e19a
Price: 516 €
Supplier: Bioss Polyclonal Antibodies
Product name: Anti-AMPK alpha 2 (Ser491), ALEXA Fluor 594
Quantity: 100 microliters
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More details :

Type: Conjugated Primary Antibody
Conjugated with: 594, ALEXA FLUOR®
Host organism: Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide: AMPK alpha 2 Ser491
Specificity: This antibody reacts specifically with AMPK alpha 2 (Ser491)
Modification: Phosphorylation
Modification site: Ser491
Clonality: Polyclonal Antibody
Clone: Polyclonal Antibodies
Concentration: 1ug per 1ul
Antigen Source: KLH conjugated synthetic phosphopeptide derived from human AMPK alpha 2 around the phosphorylation site of Ser491
Gene ID: 5563
Applications: IF(IHC-P)
Applications with corresponding dilutions: IF(IHC-P)(1:50-200)
Cross reactive species: Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details: However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information: AMPK is a heterotrimer consisting of an alpha catalytic subunit, AMPK is activated, AMPK is an important energy-sensing enzyme that monitors cellular energy status, In response to cellular metabolic stresses, Jul 2008], Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia, [provided by RefSeq, and non-catalytic beta and gamma subunits, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol, The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK)
Purification method: Purified by Protein A
Storage: 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission: 590nm/617nm
Synonyms: AMPK AMPKa2
Also known as: AMPK alpha 2 (Ser491) Antibody
Other name: Anti-AMPK alpha 2 (Ser491)
Advisory: For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties: For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: AMPK alpha 2 (Ser491)
Short name: Anti-AMPK alpha 2 (Ser491) Fluor 594
Label: ALEXA
Alternative name: ALEXA Fluor 594, antibody to-AMPK a 2 (Ser491)
Identity: 9377
Gene: PRKAA2 | More about : PRKAA2
Long gene name: protein kinase AMP-activated catalytic subunit alpha 2
Synonyms gene: PRKAA
Synonyms gene name: AMP-activated, alpha 2 catalytic subunit , protein kinase
Locus: 1p32, 2
Discovery year: 1995-12-12
GenBank acession: BC069823
Entrez gene record: 5563
Pubmed identfication: 7959015
RefSeq identity: NM_006252
Havana BLAST/BLAT: OTTHUMG00000008282

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