| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ALDH1A2 |
| Specificity: |
This antibody reacts specifically with ALDH1A2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ALDH1A2 |
| Gene ID: |
8854 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ALDH genes upregulate as a part of the oxidative stress response, ALDH-E1 or ALDH E1, ALDH1A1, ALDH1A3 (ALDH6, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3, ALDH3, ALDH3A1 (stomach type, ALDHII, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde, RALDH3, The ALDH1A2 (RALDH2, There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space, aldehyde dehydrogenase cytosolic, aldehyde dehydrogenase family 1 member A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents, and lipid peroxidation, biogenic amines and neurotransmitters, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA), metabolism of corticosteroids, stomach and kidney, 5 kb most abundant in salivary gland, Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RALDH2 |
| Also known as: |
ALDH1A2 Polyclonal Antibody |
| Other name: |
Anti-ALDH1A2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ALDH1A2 |
| Short name: |
Anti-ALDH1A2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member A2 (polyclonal), antibody to-aldehyde dehydrogenase 1 family |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ALDH1A2 and IDBG-13982 and ENSG00000128918 and 101928635, ALDH1A2 and IDBG-646601 and ENSBTAG00000010119 and 535075, Aldh1a2 and IDBG-182855 and ENSMUSG00000013584 and 19378, Cytoplasm, NAD or NADP as acceptor, NAD or NADP as acceptor and also this GO :0016918 : retinal binding, NAD or NADP as acceptor and molecular function this GO :0016918 and retinal binding and molecular function this GO :0021915 and neural tube development and biological process this GO :0021983 and pituitary gland development and biological process this GO :0030182 and neuron differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030900 and forebrain development and biological process this GO :0030902 and hindbrain development and biological process this GO :0031016 and pancreas development and biological process this GO :0031076 and embryonic camera-type eye development and biological process this GO :0032355 and response to estradiol and biological process this GO :0033189 and response to vitamin A and biological process this GO :0034097 and response to cytokine and biological process this GO :0035115 and embryonic forelimb morphogenesis and biological process this GO :0035799 and ureter maturation and biological process this GO :0042572 and retinol metabolic process and biological process this GO :0042573 and retinoic acid metabolic process and biological process this GO :0042574 and retinal metabolic process and biological process this GO :0042904 and 9-cis-retinoic acid biosynthetic process and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048566 and embryonic digestive tract development and biological process this GO :0048738 and cardiac muscle tissue development and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060324 and face development and biological process this GO :0071300 and cellular response to retinoic acid and biological process, RALDH(II) and RALDH2 and RALDH2-T, acting on the aldehyde or oxo group of donors, acting on the aldehyde or oxo group of donors, acting on the aldehyde or oxo group of donors, member A2, oxidoreductase activity, this GO :0001568 and blood vessel development and biological process this GO :0001758 and retinal dehydrogenase activity and molecular function this GO :0001822 and kidney development and biological process this GO :0001889 and liver development and biological process this GO :0001936 and regulation of endothelial cell proliferation and biological process this GO :0002138 and retinoic acid biosynthetic process and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0004028 and 3-chloroallyl aldehyde dehydrogenase activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006776 and vitamin A metabolic process and biological process this GO :0007494 and midgut development and biological process this GO :0008152 and metabolic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009855 and determination of bilateral symmetry and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0014032 and neural crest cell development and biological process this GO :0016331 and morphogenesis of embryonic epithelium and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0016620 and oxidoreductase activity, this GO :0001758 : retinal dehydrogenase activity, this GO :0001758 : retinal dehydrogenase activity and also this GO :0004028 : 3-chloroallyl aldehyde dehydrogenase activity and also this GO :0016491 : oxidoreductase activity and also this GO :0016620 : oxidoreductase activity, this GO :0004028 : 3-chloroallyl aldehyde dehydrogenase activity, this GO :0016491 : oxidoreductase activity, this GO :0016620 : oxidoreductase activity, this GO :0016918 : retinal binding, 8854, aldehyde dehydrogenase 1 family |
| Identity: |
15472 |
| Gene: |
ALDH1A2 |
More about : ALDH1A2 |
| Long gene name: |
aldehyde dehydrogenase 1 family member A2 |
| Synonyms gene name: |
aldehyde dehydrogenase 1 family, member A2 |
| Synonyms name: |
retinaldehyde dehydrogenase 2 |
| Locus: |
15q21, 3 |
| Discovery year: |
2001-03-30 |
| GenBank acession: |
AB015228 |
| Entrez gene record: |
8854 |
| Pubmed identfication: |
9819382 |
| Classification: |
Aldehyde dehydrogenases |
| Havana BLAST/BLAT: |
OTTHUMG00000132624 |