| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ADH6 |
| Specificity: |
This antibody reacts specifically with ADH6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ADH6 |
| Gene ID: |
130 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors, ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, Localized to the cytoplasm and expressed in the stomach and liver, Multiple isoforms of ADH6 exist due to alternative splicing events, This family of enzymes functions to metabolize a wide variety of substrates such as retinol, aliphatic alcohols and lipid peroxidation products, also known as ADH-5, ethanol, hydroxysteroids, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family, suggesting that expression of ADH6 may be under hormonal control, ADH6 (alcohol dehydrogenase 6) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ADH-5 |
| Also known as: |
ADH6 Polyclonal Antibody |
| Other name: |
Anti-ADH6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ADH6 |
| Short name: |
Anti-ADH6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ADH6 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
255 |
| Gene: |
ADH6 |
More about : ADH6 |
| Long gene name: |
alcohol dehydrogenase 6 (class V) |
| Locus: |
4q23 |
| Discovery year: |
1992-04-07 |
| GenBank acession: |
AK092768 |
| Entrez gene record: |
130 |
| Pubmed identfication: |
1881901 |
| RefSeq identity: |
NM_000672 |
| Classification: |
Alcohol dehydrogenases |
| Havana BLAST/BLAT: |
OTTHUMG00000131024 |