| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Actin Regulatory Protein CAPG |
| Specificity: |
This antibody reacts specifically with Actin Regulatory Protein CAPG |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Actin Regulatory Protein CAPG |
| Gene ID: |
822 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ADF, Both muscular (CDh) and non-muscular (CD1) forms of Caldesmon bind to Actin as well as to Calmodulin and Myosin, CDh is expressed predominantly on thin filaments in smooth muscle, CapG, CapG, CapG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function, Dematin and Cofilin are differentially expressed Actin-binding proteins, Filamin 1, Gelsolin, It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm, Nebulin, Plastin, The interactions of CapG with Actin may be important in the regulation of nuclear and cytoplasmic structures, also designated Actin-regulatory protein and macrophage-capping protein, but does not sever preformed ones, is a macrophage-specific protein that reversibly blocks the barbed ends of Actin filaments, whereas CD1 is widely expressed in non-muscle tissues and cells, Caldesmon |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MCP |
| Also known as: |
Actin Regulatory Protein CAPG Antibody |
| Other name: |
Anti-Actin Regulatory Protein CAPG |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Actin Regulatory Protein CAPG |
| Short name: |
Fluor 594, Anti-Actin Regulatory Protein CAPG |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Actin Regulatory Protein CAPG |
| Identity: |
1474 |
| Gene: |
CAPG |
More about : CAPG |
| Long gene name: |
capping actin protein, gelsolin like |
| Synonyms gene: |
AFCP |
| Synonyms gene name: |
capping protein (actin filament), gelsolin-like |
| Synonyms name: |
macrophage capping protein |
| Locus: |
2p11, 2 |
| Discovery year: |
1993-12-14 |
| GenBank acession: |
M94345 |
| Entrez gene record: |
822 |
| Pubmed identfication: |
1322908 12754261 |
| RefSeq identity: |
NM_001747 |
| Classification: |
Gelsolin/villins |
| Havana BLAST/BLAT: |
OTTHUMG00000130183 |