| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LTBP1 |
| Specificity: |
This antibody reacts specifically with LTBP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LTBP1 |
| Gene ID: |
4052 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cleavage of LTBP results in LTBP-1, LTBP-1 mRNA is enriched in ovarian carcinoma tissues and highly expressed in serous and mucinous adenocarcinomas, LTBP-1 serves as an anchor for latent TGF-beta in the extracellular matrix and is a component of microfibrillar structures, a heavy glycoprotein, is part of the platelet-derived TGF-beta 1 complex, which may sequester latent TGF-beta in the extracellular matrix and regulate its activation, Latent transforming growth factor-beta 1 binding protein 1 (LTBP-1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
LTBP1 Polyclonal Antibody |
| Other name: |
Anti-LTBP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LTBP1 |
| Short name: |
Anti-LTBP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-latent transforming growth factor b binding protein 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, Extracellular, LTBP1 and IDBG-43767 and ENSG00000049323 and 4052, Ltbp1 and IDBG-198219 and ENSMUSG00000001870 and 268977, this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0007178 and transmembrane receptor protein serine/threonine kinase signaling pathway and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0035583 and sequestering of TGFbeta in extracellular matrix and biological process this GO :0050431 and transforming growth factor beta binding and molecular function, this GO :0005024 : transforming growth factor beta-activated receptor activity, this GO :0005024 : transforming growth factor beta-activated receptor activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0050431 : transforming growth factor beta binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0050431 : transforming growth factor beta binding, transforming growth factor beta binding, 89253 and IDBG-632153 and ENSBTAG00000019839 and 510559, latent transforming growth factor beta binding protein 1 |
| Identity: |
6714 |
| Gene: |
LTBP1 |
More about : LTBP1 |
| Long gene name: |
latent transforming growth factor beta binding protein 1 |
| Synonyms name: |
TGF-beta1-BP-1 |
| Locus: |
2p22, 3 |
| Discovery year: |
1993-09-20 |
| Entrez gene record: |
4052 |
| Pubmed identfication: |
2350783 11104663 |
| RefSeq identity: |
NM_206943 |
| Classification: |
Latent transforming growth factor beta binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000152118 |