| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RBM15/SPEN |
| Specificity: |
This antibody reacts specifically with RBM15/SPEN |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RBM15 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Chromosomal aberrations involving the RBM15 gene, Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, RBM15 is subject to post-translational phosphorylation, may be associated with the development of acute megakaryoblastic leukemia, possibly via interactions with RNA and spliceosome components, probably by ATM or ATR, which localizes to human chromosome 1, RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
OTT OTT1 |
| Also known as: |
RBM15/SPEN Polyclonal Antibody |
| Other name: |
Anti-RBM15/SPEN Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RBM15/SPEN |
| Short name: |
Anti-RBM15/SPEN (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RNA binding motif protein 15/SPEN (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
RBM15 and IDBG-100966 and ENSG00000162775 and 64783, RBM15 and IDBG-648900 and ENSBTAG00000012555 and 541044, Rbm15 and IDBG-185199 and ENSMUSG00000048109 and 229700, nuclei, poly(A) RNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000166 and nucleotide binding and molecular function this GO :0001569 and patterning of blood vessels and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0007221 and positive regulation of transcription of Notch receptor target and biological process this GO :0016032 and viral process and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0048536 and spleen development and biological process this GO :0060412 and ventricular septum morphogenesis and biological process this GO :0060674 and placenta blood vessel development and biological process, this GO :0000166 : nucleotide binding, this GO :0000166 : nucleotide binding and also this GO :0003676 : nucleic acid binding and also this GO :0005515 : protein binding and also this GO :0044822 : poly(A) RNA binding, this GO :0003676 : nucleic acid binding, this GO :0005515 : protein binding, this GO :0044822 : poly(A) RNA binding, RNA binding motif protein 15 |
| Identity: |
14959 |
| Gene: |
RBM15 |
More about : RBM15 |
| Long gene name: |
RNA binding motif protein 15 |
| Synonyms name: |
one twenty-two |
| Locus: |
1p13, 3 |
| Discovery year: |
2001-05-10 |
| GenBank acession: |
AF368063 |
| Entrez gene record: |
64783 |
| Pubmed identfication: |
11431691 11344311 |
| RefSeq identity: |
NM_022768 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000011284 |