| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RAB23 |
| Specificity: |
This antibody reacts specifically with RAB23 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RAB23 |
| Gene ID: |
51715 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport, Mutations in the gene encoding Rab 23 may result in Carpenter syndrome, Rab 23, Rab 23 is believed to play a role in intracellular protein transportation and signal transduction mediated by small GTPases, Rab proteins are also an integral part of endocytic pathways, Ral/Rec and Rho/Rab subfamilies, Rap, The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function, a condition characterized by obesity, also known as ACPS2 (acrocephalopolysyndactyly type 2), also known as HSPC137, cardiac defects, is a 237 amino acid member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane, polysyndactyly and craniosynostosis, The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
RAB23 Polyclonal Antibody |
| Other name: |
Anti-RAB23 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RAB23 |
| Short name: |
Anti-RAB23 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RAB23 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14263 |
| Gene: |
RAB23 |
More about : RAB23 |
| Long gene name: |
RAB23, member RAS oncogene family |
| Locus: |
6p12, 1-p11, 2 |
| Discovery year: |
2000-12-18 |
| GenBank acession: |
AB034244 |
| Entrez gene record: |
51715 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000014918 |