| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IPMK |
| Specificity: |
This antibody reacts specifically with IPMK |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IPMK |
| Gene ID: |
253430 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cockayne syndrome and Tetrahydrobiopterin deficiency, However, IPMK displays a preference for inositol-1, IPMK is localized to the nucleus, IPMK is ubiquitously expressed with the highest expression in skeletal muscle, Notably, The gene encoding IPMK maps to human chromosome 10, disorders linked to genes on chromosome 10 include Cowden syndrome, kidney, liver, lung, peripheral blood leukocytes, placenta, spleen and colon, where it may play a role in the regulation of calcium release from intracellular stores and has been implicated as a drug target for cancer therapies, which contains over 800 genes, 3, 3, 4, 4, 4, 4, 5)P3) and inositol 1, 5-trisphosphate (Ins(1, 6)P4), 6-tetrakisphosphate (Ins(1, Inositol polyphosphate multikinase (IPMK) belongs to the inositol phosphokinase (IPK) family and is characterized as having a broad substrate specificity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
IPMK Polyclonal Antibody |
| Other name: |
Anti-IPMK Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IPMK |
| Short name: |
Anti-IPMK (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-IPMK (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
20739 |
| Gene: |
IPMK |
More about : IPMK |
| Long gene name: |
inositol polyphosphate multikinase |
| Locus: |
10q21, 1 |
| Discovery year: |
2004-02-05 |
| GenBank acession: |
AF432853 |
| Entrez gene record: |
253430 |
| Pubmed identfication: |
12223481 12027805 |
| RefSeq identity: |
NM_152230 |
| Havana BLAST/BLAT: |
OTTHUMG00000018268 |