| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ABCB7 |
| Specificity: |
This antibody reacts specifically with ABCB7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ABCB7 |
| Gene ID: |
22 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
12q11-q12, 1p22-p21 and 14q24, A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol and maps to human chromosome Xq13, ABCD1â, ABCD2 in mouse, ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors (5), ABCD4 localizes to peroxisomes (1), All four proteins are ABC half-transporters, PMP22 and ABCD3 (5), The genes which encode ABCD1â, The peroxisomal membrane comprises 2 quantitatively major proteins, a peroxisomal disorder which affects lipid storage (2, is expressed at high levels in the brain and adrenal organs, respectively (3, which are adversely affected in X-ALD (4), which dimerize to form an active transporter (1), &euro, &euro, &euro, &ldquo, &ldquo, &ldquo, 1-q13, 3, 3 (9), 3), 4 map to human chromosome Xq28, 4 that are known to be present in the human peroxisome membrane (1), 6â, 8), The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
EST140535 Atm1p ASAT |
| Also known as: |
ABCB7 Polyclonal Antibody |
| Other name: |
Anti-ABCB7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ABCB7 |
| Short name: |
Anti-ABCB7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ABCB7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
48 |
| Gene: |
ABCB7 |
More about : ABCB7 |
| Long gene name: |
ATP binding cassette subfamily B member 7 |
| Synonyms gene: |
ABC7 |
| Synonyms gene name: |
ATP-binding cassette, member 7 , sub-family B (MDR/TAP) |
| Locus: |
Xq13, 3 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
AF038950 |
| Entrez gene record: |
22 |
| Pubmed identfication: |
9143506 |
| RefSeq identity: |
NM_004299 |
| Classification: |
ATP binding cassette subfamily B |
| Havana BLAST/BLAT: |
OTTHUMG00000021862 |
| Locus Specific Databases: |
Mental Retardation database |