| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PTCHD2/DISP3 |
| Specificity: |
This antibody reacts specifically with PTCHD2/DISP3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PTCHD2/DISP3 |
| Gene ID: |
57540 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Existing as two alternatively spliced isoforms, Expressed in retina, PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol, PTCHD2 overexpression leads to increased cholesterol levels, brain and testis, suggesting that PTCHD2 may play a role in cholesterol homeostasis, 22, 392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family, PTCHD2 is a 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1337 |
| Also known as: |
PTCHD2/DISP3 Polyclonal Antibody |
| Other name: |
Anti-PTCHD2/DISP3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PTCHD2/DISP3 |
| Short name: |
Anti-PTCHD2/DISP3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PTCHD2/DISP3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
29251 |
| Gene: |
DISP3 |
More about : DISP3 |
| Long gene name: |
dispatched RND transporter family member 3 |
| Synonyms gene: |
PTCHD2 |
| Synonyms gene name: |
patched domain containing 2 |
| Synonyms name: |
dispatched homolog 3 (Drosophila) |
| Locus: |
1p36, 22 |
| Discovery year: |
2005-05-24 |
| GenBank acession: |
AB037758 |
| Entrez gene record: |
57540 |
| Pubmed identfication: |
15738394 25281927 |
| RefSeq identity: |
XM_052561 |
| Havana BLAST/BLAT: |
OTTHUMG00000002074 |