| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
USE1 |
| Specificity: |
This antibody reacts specifically with USE1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human USE1 |
| Gene ID: |
55850 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs), For membrane-directed proteins this process is believed to be carried out via vesicular transport, RINT-1 and Syntaxin 18, RINT-1 and USE1 dissociate from Syntaxin 18, Three named isoforms exist for USE1 as a result of alternative splicing events, USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane, Unconventional SNARE in the ER 1, Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, after covalent modification, also known as USE1 or protein p31, delivers them to their destination in the cell, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, In eukaryotic cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ13855 USE1 |
| Also known as: |
USE1 Polyclonal Antibody |
| Other name: |
Anti-USE1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
USE1 |
| Short name: |
Anti-USE1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-USE1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
25847 |
| Gene: |
UBE2Z |
More about : UBE2Z |
| Long gene name: |
ubiquitin conjugating enzyme E2 Z |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2Z |
| Synonyms name: |
UBA6-specific enzyme E2 |
| Locus: |
17q21, 32 |
| Discovery year: |
2005-12-15 |
| GenBank acession: |
BC015890 |
| Entrez gene record: |
65264 |
| Pubmed identfication: |
17597759 |
| RefSeq identity: |
NM_023079 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000150521 |