| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CDX4 |
| Specificity: |
This antibody reacts specifically with CDX4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CDX4 |
| Gene ID: |
1046 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, Cdx4 is a direct target of the canonical Wnt pathway, Cdx4 is a major positive regulator of the expression of all Hox family members, Due to its critical role as a regulator, Hox genes play a fundamental role in the development of the vertebrate central nervous system, The loss of Cdx4 can result in the development of an expanded hindbrain, The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes, axial skeleton, gut, heart, limbs, urogenital tract and external genitalia, which are homologs of the Drosophila â, while the overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord, &euro, &euro, &oelig, Cdx1, caudalâ, gene required for anterior-posterior regional identity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
CDX4 Polyclonal Antibody |
| Other name: |
Anti-CDX4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CDX4 |
| Short name: |
Anti-CDX4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CDX4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1808 |
| Gene: |
CDX4 |
More about : CDX4 |
| Long gene name: |
caudal type homeobox 4 |
| Synonyms gene name: |
caudal type homeo box transcription factor 4 |
| Locus: |
Xq13, 2 |
| Discovery year: |
1995-06-14 |
| GenBank acession: |
AF029879 |
| Entrez gene record: |
1046 |
| Pubmed identfication: |
7655457 |
| RefSeq identity: |
NM_005193 |
| Classification: |
HOXL subclass homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000021831 |