| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PREI3/Phocein |
| Specificity: |
This antibody reacts specifically with PREI3/Phocein |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PREI3/Phocein |
| Gene ID: |
25843 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Due to its association with Dynamin via direct interactions with nucleotide diphosphate kinase (NDPK) and Eps15, Phocein belongs to the MOB1/phocein family and is phosphorylated on serine residues, Phocein has been implicated in vesicular trafficking, Phocein is a widely expressed, Phocein is the major partner of the striatin family members, Phocein is usually associated with membranes but can be present in the cytosol, The sequence of Phocein has limited homology to the sigma subunits from Clathrin adaptor complexes and contains an additional stretch bearing a putative SH3-binding domain, acting in particular in the endocytic process, highly conserved intracellular protein, where it behaves as a protein complex, which are scaffolding proteins involved in signaling and trafficking, Phocein is a 225 amino acid protein encoded by the human gene MOBKL3 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MOB3 DKFZP564M112 CGI-95 2C4D PHOCN |
| Also known as: |
PREI3/Phocein Polyclonal Antibody |
| Other name: |
Anti-PREI3/Phocein Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PREI3/Phocein |
| Short name: |
Anti-PREI3/Phocein (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PREI3/Phocein (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17261 |
| Gene: |
MOB4 |
More about : MOB4 |
| Long gene name: |
MOB family member 4, phocein |
| Synonyms gene: |
PREI3 MOBKL3 |
| Synonyms gene name: |
Mps One Binder kinase activator-like 3 (yeast) , preimplantation protein 3 MOB1 |
| Synonyms name: |
Mob-like protein , phocein phocein |
| Locus: |
2q33, 1 |
| Discovery year: |
2002-01-16 |
| GenBank acession: |
AF151853 |
| Entrez gene record: |
25843 |
| Pubmed identfication: |
17853115 10810093 11230166 11319234 |
| RefSeq identity: |
NM_015387 |
| Classification: |
STRIPAK complex MOB kinase activators |
| Havana BLAST/BLAT: |
OTTHUMG00000132748 |