| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PSMA4 |
| Specificity: |
This antibody reacts specifically with PSMA4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PSMA4 |
| Gene ID: |
5685 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
All of the subunits fall into one of two types: alpha subunits, The 20S Proteasome core is hollow and forms an enclosed cavity, The 20S Proteasome core particle contains many subunits, The main function of proteasomes is to degrade unnecessary or damaged proteins by proteolysis, The most common form of the proteasome, The outer two rings in the proteasome consist of seven ?subunits each, and in some bacteria, and the inner two rings each consist of seven beta subunits, as well as openings at the two ends to allow the target protein to enter, contains one 20S Proteasome core particle structure and two 19S regulatory caps, depending on the organism, known as the 26S Proteasome, or beta subunits, serve as docking domains for the regulatory particles and exterior gates blocking unregulated access to the interior cavity, where proteins are degraded, which are predominantly catalytic, which are structural, The proteasome represents a large protein complex that exists inside all eukaryotes and archaea |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HC9 HsT17706 |
| Also known as: |
PSMA4 Polyclonal Antibody |
| Other name: |
Anti-PSMA4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PSMA4 |
| Short name: |
Anti-PSMA4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
4 (polyclonal), ALEXA Fluor 594, a classification, macropain) subunit, antibody to-proteasome (prosome |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
4, HC9 and HsT17706 and PSC9, PSMA4 and IDBG-24777 and ENSG00000041357 and 5685, PSMA4 and IDBG-631088 and ENSBTAG00000014440 and 510423, Psma4 and IDBG-167326 and ENSMUSG00000032301 and 26441, TAP-dependent and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004298 and threonine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005839 and proteasome core complex and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, alpha type, alpha-subunit complex and cellular component this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, macropain) subunit, nuclei, protein binding, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0019773 and proteasome core complex, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0000932 and cytoplasmic mRNA processing body and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004298 : threonine-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0004298 : threonine-type endopeptidase activity, this GO :0005515 : protein binding, proteasome (prosome |
| Identity: |
9533 |
| Gene: |
PSMA4 |
More about : PSMA4 |
| Long gene name: |
proteasome subunit alpha 4 |
| Synonyms gene name: |
4 , alpha type, macropain) subunit, proteasome (prosome |
| Locus: |
15q25, 1 |
| Discovery year: |
1995-05-03 |
| GenBank acession: |
BC005361 |
| Entrez gene record: |
5685 |
| Pubmed identfication: |
2025653 |
| RefSeq identity: |
NM_002789 |
| Classification: |
Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000143859 |