| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NAC1/BTBD14B |
| Specificity: |
This antibody reacts specifically with NAC1/BTBD14B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NAC1/BTBD14B |
| Gene ID: |
112939 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BEND8 or NAC1, BTBD14B (BTB/POZ domain-containing protein 14B), BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines, BTBD14B is overexpressed in multiple carcinomas, Existing as a homooligomer that interacts with HDAC3 and HDAC4, Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function, also known as NACC1 (nucleus accumbens associated 1), is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain, suggesting a role in tumor development and metastasis, NAC1 is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NAC1 NAC-1 BEND8 BTBD30 |
| Also known as: |
NAC1/BTBD14B Polyclonal Antibody |
| Other name: |
Anti-NAC1/BTBD14B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NAC1/BTBD14B |
| Short name: |
Anti-NAC1/BTBD14B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NAC1/BTBD14B (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
20967 |
| Gene: |
NACC1 |
More about : NACC1 |
| Long gene name: |
nucleus accumbens associated 1 |
| Synonyms gene: |
BTBD14B |
| Synonyms gene name: |
BEN and BTB (POZ) domain containing , BTB (POZ) domain containing 14B nucleus accumbens associated 1 |
| Synonyms name: |
nucleus accumbens associated 1 BEN domain containing 8 |
| Locus: |
19p13, 13 |
| Discovery year: |
2003-12-15 |
| GenBank acession: |
AF395817 |
| Entrez gene record: |
112939 |
| Pubmed identfication: |
12477932 |
| RefSeq identity: |
NM_052876 |
| Classification: |
BTB domain containing BEN domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180748 |