| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
XRCC1 |
| Specificity: |
This antibody reacts specifically with XRCC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Helical |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human XRCC1 |
| Gene ID: |
7515 |
| Swiss Prot: |
P18887 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
XRCC1 Polyclonal Antibody |
| Other name: |
Anti-XRCC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
XRCC1 |
| Short name: |
Anti-XRCC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-X-ray repair complementing defective repair in Chinese hamster cells 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
RCC, XRCC1 and IDBG-55268 and ENSG00000073050 and 7515, XRCC1 and IDBG-639023 and ENSBTAG00000016268 and 616905, Xrcc1 and IDBG-155000 and ENSMUSG00000051768 and 22594, nuclei, protein binding, this GO :0000012 and single strand break repair and biological process this GO :0001666 and response to hypoxia and biological process this GO :0003684 and damaged DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006284 and base-excision repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0010033 and response to organic substance and biological process this GO :0021766 and hippocampus development and biological process this GO :0042493 and response to drug and biological process, this GO :0003684 : damaged DNA binding, this GO :0003684 : damaged DNA binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, X-ray repair complementing defective repair in Chinese hamster cells 1 |
| Identity: |
12828 |
| Gene: |
XRCC1 |
More about : XRCC1 |
| Long gene name: |
X-ray repair cross complementing 1 |
| Synonyms gene: |
RCC |
| Synonyms gene name: |
X-ray repair complementing defective repair in Chinese hamster cells 1 |
| Locus: |
19q13, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M36089 |
| Entrez gene record: |
7515 |
| Pubmed identfication: |
2247054 |
| RefSeq identity: |
NM_006297 |
| Havana BLAST/BLAT: |
OTTHUMG00000182699 |
| Locus Specific Databases: |
LRG_784 |