| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ASPH/Aspartate beta hydroxylase |
| Specificity: |
This antibody reacts specifically with ASPH/Aspartate beta hydroxylase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ASPH/Aspartate beta hydroxylase |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ASPH, ASPH can be processed into two different forms, ASPH specifically hydroxylates an Asp or Asn residue in the epidermal growth factor-like (EGF) domains of several proteins, In the lumen of the endoplasmic reticulum, Junctin, Located in the endoplasmic reticulum, The ASPH gene encodes 3 proteins, These ASPH gene products are expressed as five transcript variants that differ by their roles in calcium storage and release, While all ASPH variants are expressed in skeletal muscle, and Junctate (or Humbug), and kidney tissues, and tissue specificity, brain, hydroxylation capabilities, liver, lung, only some are detected in heart, pancreas, placenta, that differ significantly in their C-terminal domains, using iron as a cofactor, Aspartyl/asparaginyl beta-hydroxylase (ASPH) is a widely-expressed type II membrane protein involved in calcium homeostasis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CASQ2BP1 BAH JCTN HAAH |
| Also known as: |
ASPH/Aspartate beta hydroxylase Antibody |
| Other name: |
Anti-ASPH/Aspartate beta hydroxylase |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
ASPH/Aspartate beta hydroxylase |
| Short name: |
Fluor 594, Anti-ASPH/Aspartate beta hydroxylase |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ASPH/Aspartate b hydroxylase |
| Identity: |
757 |
| Gene: |
ASPH |
More about : ASPH |
| Long gene name: |
aspartate beta-hydroxylase |
| Synonyms name: |
junctin humbug junctate |
| Locus: |
8q12, 3 |
| Discovery year: |
1995-06-13 |
| GenBank acession: |
AF224468 |
| Entrez gene record: |
444 |
| Pubmed identfication: |
7821814 10974562 |
| RefSeq identity: |
NM_004318 |
| Havana BLAST/BLAT: |
OTTHUMG00000164375 |