| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
P2RX6 |
| Specificity: |
This antibody reacts specifically with P2RX6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human P2RX6 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
P2X receptors are expressed in a wide variety of tissues, P2X1-P2X7, The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP, The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, The seven P2X receptors, They are characterized by intracellular amino- and carboxy-termini, bladder, colon, form either homomeric or heteromeric channels or both, including neurons, pancreas, prostate, testis and ovary, which acts as a neurotransmitter, The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
P2XM MGC129625 P2X6 |
| Also known as: |
P2RX6 Polyclonal Antibody |
| Other name: |
Anti-P2RX6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
P2RX6 |
| Short name: |
Anti-P2RX6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-P2RX6 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8538 |
| Gene: |
P2RX6 |
More about : P2RX6 |
| Long gene name: |
purinergic receptor P2X 6 |
| Synonyms gene: |
P2RXL1 |
| Synonyms gene name: |
6 , ligand-gated ion channel, orphan receptor purinergic receptor P2X, purinergic receptor P2X-like 1 |
| Locus: |
22q11, 21 |
| Discovery year: |
1999-02-24 |
| Entrez gene record: |
9127 |
| Pubmed identfication: |
9242461 10591208 8786426 |
| RefSeq identity: |
NM_005446 |
| Classification: |
Purinergic receptors P2X |
| Havana BLAST/BLAT: |
OTTHUMG00000150689 |