| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
5HT2B Receptor/SR-2B |
| Specificity: |
This antibody reacts specifically with 5HT2B Receptor/SR-2B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human 5HT2B Receptor/SR-2B |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In platelets and gut, In the CNS, SR-2A, SR-2A has a specific role in tracheal smooth muscle contraction, SR-2B and SR-2C, SR-2B is expressed in embryonic and adult cardiovascular tissues, SR-2C is thought to mediate the effects of atypical antipsychotic drugs, Serotonin mediates its effects through several of G protein coupled receptors, The SR-2 receptors are comprised of three subtypes, a hormone and a mitogen, and it is also thought to play a role in several psychiatric disorders, and it is predominantly expressed in the gut, appetite, behavior and drug abuse, bronchoconstriction and mediating aldosterone production, designated 5-HT receptors or alternatively SR receptors, gut and brain and plays an important role in the pathology of cardiac disorders, including anxiety, including depression and schizophrenia, platelets and central nervous system (CNS), respectively, serotonin modulates several processes, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, sleep, which activate phospholipase C and release intracellular stores of calcium in response to serotonin, Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
5 HT 2B receptor, 5 HT2B, 5 HT2B, 5 hydroxytryptamine 2B receptor, 5 hydroxytryptamine receptor 2B, 5 hydroxytryptamine serotonin receptor 2B, 5 hydroxytryptamine serotonin receptor 2B G protein coupled, 5-HT-2B, 5-HT2B, 5-hydroxytryptamine receptor 2B, 5HT2B, 5HT2B_HUMAN, 5HT2F, Htr 2b, Htr2b, NP75 protein, SEROTONIN 5HT2B RECEPTOR, Serotonin receptor 2B, Stomach fundus serotonin receptor, 5 HT 2B |
| Also known as: |
5HT2B Receptor/SR-2B Polyclonal Antibody |
| Other name: |
Anti-5HT2B Receptor/SR-2B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
5HT2B Receptor/SR-2B |
| Short name: |
Anti-5HT2B Receptor/SR-2B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-5HT2B Receptor/SR-2B (polyclonal) |
| Alternative technique: |
polyclonals |