| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RITA/C12orf52 |
| Specificity: |
This antibody reacts specifically with RITA/C12orf52 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RITA/C12orf52 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, Noonan syndrome, SH-PTP2, The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization, Trisomy 12p leads to facial development defects, achondrogenesis and Kniest dysplasia, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction, chromosome 12 makes up about 4, is caused by a mutant form of PTPN11 gene product, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy, which includes heart and facial developmental defects among the primary symptoms, 100 genes within 132 million bases, 5% of the human genome, Encoding over 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RITA ZNF463 ZNF361 |
| Also known as: |
RITA/C12orf52 Polyclonal Antibody |
| Other name: |
Anti-RITA/C12orf52 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RITA/C12orf52 |
| Short name: |
Anti-RITA/C12orf52 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RITA/C12orf52 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
15489 |
| Gene: |
ZNF331 |
More about : ZNF331 |
| Long gene name: |
zinc finger protein 331 |
| Synonyms name: |
rearranged in thyroid adenomas |
| Locus: |
19q13 |
| Discovery year: |
2003-10-06 |
| GenBank acession: |
AF251515 |
| Entrez gene record: |
55422 |
| RefSeq identity: |
NM_018555 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000163019 |
| Locus Specific Databases: |
LRG_1068 |