| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PNMA1 |
| Specificity: |
This antibody reacts specifically with PNMA1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PNMA1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
MA1, MA2, MA2 and MA3, MA3 is highly expressed in brain and testis and is expressed at low levels in heart, Most PNDs are caused by an immune response against onconeural antigens, The most common neoplasm among young male patients is testicular cancer, The paraneoplastic antigen MA family contains three known members: MA1, also designated neuron- and testis-specific protein 1, also designated onconeuronal antigen MA2, an underlying neoplasm, but the leading cause among other patients is lung cancer, causing progressive neurological damage, is a nucleolar protein expressed in brain and testis, is a nucleolar protein in normal cells but localizes to the cytoplasm of tumor cells, or associated with, trachea and kidney, Paraneoplastic neurological disorders (PNDs) are rare syndromes that are caused by |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MA1 |
| Also known as: |
PNMA1 Polyclonal Antibody |
| Other name: |
Anti-PNMA1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PNMA1 |
| Short name: |
Anti-PNMA1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PNMA1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9158 |
| Gene: |
PNMA1 |
More about : PNMA1 |
| Long gene name: |
paraneoplastic Ma antigen 1 |
| Synonyms gene name: |
paraneoplastic antigen MA1 |
| Locus: |
14q24, 3 |
| Discovery year: |
1999-09-17 |
| GenBank acession: |
AF037364 |
| Entrez gene record: |
9240 |
| Pubmed identfication: |
10050892 |
| RefSeq identity: |
NM_006029 |
| Classification: |
Paraneoplastic Ma antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000169183 |