| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Neuro D2 |
| Specificity: |
This antibody reacts specifically with Neuro D2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Neuro D2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Class A proteins include the ubiquitously expressed E-box binding factors, ITF-2 and HEB, NEUROD2 or bHLHa1, Neuro D2 (neurogenic differentiation 2), Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation, also known as NDRF, are transiently expressed and exhibit a much more limited tissue distribution, both of which work together to activate DNA transcription, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, myogenin and Neuro D (BETA2), namely E2A, playing an important role in the maintenance and determination of cell fate, such as MyoD, while class B proteins, Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Neuro D2 Polyclonal Antibody |
| Other name: |
Anti-Neuro D2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
D2 |
| Short name: |
Anti-Neuro D2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Neuro D2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1583 |
| Gene: |
CCND2 |
More about : CCND2 |
| Long gene name: |
cyclin D2 |
| Synonyms name: |
G1/S-specific cyclin D2 |
| Locus: |
12p13, 32 |
| Discovery year: |
1991-12-10 |
| GenBank acession: |
AF518005 |
| Entrez gene record: |
894 |
| Pubmed identfication: |
1386335 |
| RefSeq identity: |
NM_001759 |
| Classification: |
Cyclins |
| Havana BLAST/BLAT: |
OTTHUMG00000168123 |