| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Myotrophin/GCDP |
| Specificity: |
This antibody reacts specifically with Myotrophin/GCDP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Myotrophin/GCDP |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ANF and Beta-Myosin heavy chain transcript levels, Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle, It is important in the differentiation of cerebellar neurons, Myotrophin increases protooncogene, Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta, Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2, The 117 amino acid protein has been associated with, The gene encoding for this protein localizes to chromosome 7q33, and able to induce, cardiac hypertrophy, particularly of granule cells, 5 internal 33 amino acid ankyrin repeats, Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MYOTROPHIN GCDP V-1 |
| Also known as: |
Myotrophin/GCDP Polyclonal Antibody |
| Other name: |
Anti-Myotrophin/GCDP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Myotrophin/GCDP |
| Short name: |
Anti-Myotrophin/GCDP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Myotrophin/GCDP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
15667 |
| Gene: |
MTPN |
More about : MTPN |
| Long gene name: |
myotrophin |
| Synonyms name: |
granule cell differentiation protein |
| Locus: |
7q33 |
| Discovery year: |
2001-08-16 |
| GenBank acession: |
AC015987 |
| Entrez gene record: |
136319 |
| Pubmed identfication: |
11474205 |
| RefSeq identity: |
NM_145808 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000155627 |