| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LIN7C |
| Specificity: |
This antibody reacts specifically with LIN7C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LIN7C |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Veli proteins are ubiquitously expressed with high expression in brain, Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), Velis are localized at the synaptic junctions in neurons, Velis bind to CASK, Velis contain the PDZ motif involved in recruiting cell adhesion molecules, a binding partner with a vesicle trafficking protein, a neurexin-binding protein highly concentrated in synapses, and Mint1, and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C, and channels, and testis, elegans LIN-7, liver, receptors, Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MALS-3 Lin7c LIN-7C LIN-7-C VELI3 FLJ11215 |
| Also known as: |
LIN7C Polyclonal Antibody |
| Other name: |
Anti-LIN7C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LIN7C |
| Short name: |
Anti-LIN7C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, elegans) (polyclonal), antibody to-lin-7 homolog C (C |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cell surfaces, L27 domain binding, LIN7C and IDBG-36749 and ENSG00000148943 and 55327, LIN7C and IDBG-636096 and ENSBTAG00000001460 and 510125, Lin7c and IDBG-195526 and ENSMUSG00000027162 and 22343, elegans), this GO :0002011 and morphogenesis of an epithelial sheet and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006887 and exocytosis and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0014069 and postsynaptic density and cellular component this GO :0015031 and protein transport and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0019904 and protein domain specific binding and molecular function this GO :0030165 and PDZ domain binding and molecular function this GO :0043005 and neuron projection and cellular component this GO :0045202 and synapse and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097016 and L27 domain binding and molecular function this GO :0097025 and MPP7-DLG1-LIN7 complex and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008092 : cytoskeletal protein binding and also this GO :0019904 : protein domain specific binding and also this GO :0030165 : PDZ domain binding and also this GO :0097016 : L27 domain binding, this GO :0008092 : cytoskeletal protein binding, this GO :0019904 : protein domain specific binding, this GO :0030165 : PDZ domain binding, this GO :0097016 : L27 domain binding, lin-7 homolog C (C |
| Identity: |
17789 |
| Gene: |
LIN7C |
More about : LIN7C |
| Long gene name: |
crumbs cell polarity complex component , lin-7 homolog C |
| Synonyms gene name: |
elegans) , lin-7 homolog C (C |
| Synonyms name: |
LIN-7 protein 3 |
| Locus: |
11p14 |
| Discovery year: |
2002-09-19 |
| GenBank acession: |
AK002077 |
| Entrez gene record: |
55327 |
| Pubmed identfication: |
10341223 |
| RefSeq identity: |
NM_018362 |
| Classification: |
Crumbs complex PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166193 |