| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LDB1/CLIM-2 |
| Specificity: |
This antibody reacts specifically with LDB1/CLIM-2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LDB1/CLIM-2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
LMO1 and LMO2, LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, LMO2 and the related protein LMO4 are expressed in thymic precursor cells, LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI), LMO4 is also expressed in mature T cells, NLI, The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, and Schwann cell progenitors, and the related protein CLIM-2, are nuclear factors that are characterized by a conserved LIM domain, cranial neural crest cells, dorsal limb bud mesenchyme, facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation, known also as CLIM-1, motor neurons, somite, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons, The LIM-only (LMO) proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NLI CLIM2 |
| Also known as: |
LDB1/CLIM-2 Polyclonal Antibody |
| Other name: |
Anti-LDB1/CLIM-2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LDB1/CLIM-2 |
| Short name: |
Anti-LDB1/CLIM-2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-LDB1/CLIM-2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6532 |
| Gene: |
LDB1 |
More about : LDB1 |
| Long gene name: |
LIM domain binding 1 |
| Synonyms name: |
carboxy terminal LIM domain protein 2 |
| Locus: |
10q24, 32 |
| Discovery year: |
1999-01-22 |
| GenBank acession: |
AF068652 |
| Entrez gene record: |
8861 |
| Pubmed identfication: |
9503020 9799849 |
| RefSeq identity: |
NM_001113407 |
| Havana BLAST/BLAT: |
OTTHUMG00000018950 |