| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FNBP1L/TOCA1 |
| Specificity: |
This antibody reacts specifically with FNBP1L/TOCA1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FNBP1L/TOCA1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis, TOCA-1 is involved in membrane invagination, The gene encoding TOCA-1 maps to human chromosome 1, and contains one FCH domain, as well as to cytoplasmic vesicles and the cell membrane, contains over 3, one REM repeat and one SH3 domain, tubule formation and Actin polymerization, which spans 260 million base pairs, 000 genes and comprises nearly 8% of the human genome, TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TOCA1 FLJ20275 |
| Also known as: |
FNBP1L/TOCA1 Polyclonal Antibody |
| Other name: |
Anti-FNBP1L/TOCA1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FNBP1L/TOCA1 |
| Short name: |
Anti-FNBP1L/TOCA1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-formin binding protein 1-like/TOCA1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
FNBP1L and IDBG-100334 and ENSG00000137942 and 54874, FNBP1L and IDBG-636455 and ENSBTAG00000004383 and 616665, Fnbp1l and IDBG-191729 and ENSMUSG00000039735 and 214459, Plasma membranes, lipid binding, this GO :0005515 and protein binding and molecular function this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006900 and membrane budding and biological process this GO :0006914 and autophagy and biological process this GO :0007165 and signal transduction and biological process this GO :0008289 and lipid binding and molecular function this GO :0010324 and membrane invagination and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016050 and vesicle organization and biological process this GO :0030050 and vesicle transport along actin filament and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072583 and clathrin-mediated endocytosis and biological process this GO :0097320 and membrane tubulation and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008289 : lipid binding, this GO :0008289 : lipid binding, formin binding protein 1-like |
| Identity: |
20851 |
| Gene: |
FNBP1L |
More about : FNBP1L |
| Long gene name: |
formin binding protein 1 like |
| Synonyms gene: |
C1orf39 |
| Synonyms gene name: |
chromosome 1 open reading frame 39 formin binding protein 1-like |
| Locus: |
1p22, 1 |
| Discovery year: |
2003-05-08 |
| Entrez gene record: |
54874 |
| Pubmed identfication: |
14654988 |
| RefSeq identity: |
NM_017737 |
| Classification: |
F-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000010863 |