| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PQBP1 |
| Specificity: |
This antibody reacts specifically with PQBP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PQBP1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i, PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling, PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, The human PQBP-1 gene maps to chromosome Xp11, androgen receptor and Brain-2), cerebellar cortex and olfactory bulb, huntingtin, with abundant levels in hippocampus, 23, Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders, e |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
PQBP1 Polyclonal Antibody |
| Other name: |
Anti-PQBP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PQBP1 |
| Short name: |
Anti-PQBP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PQBP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9330 |
| Gene: |
PQBP1 |
More about : PQBP1 |
| Long gene name: |
polyglutamine binding protein 1 |
| Synonyms gene: |
RENS1 MRXS8 SHS MRX55 MRX2 MRXS3 |
| Synonyms gene name: |
Sutherland-Haan X-linked mental retardation syndrome mental retardation, X-linked 2 (non-dysmorphic) , X-linked 55 mental retardation |
| Locus: |
Xp11, 23 |
| Discovery year: |
1999-01-12 |
| GenBank acession: |
AJ005893 |
| Entrez gene record: |
10084 |
| Pubmed identfication: |
9875212 15024694 14634649 |
| RefSeq identity: |
NM_001032381, 1 |
| Classification: |
X-linked mental retardation |
| Havana BLAST/BLAT: |
OTTHUMG00000024128 |
| Locus Specific Databases: |
Mental Retardation database |