| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
1, Kv1 |
| Specificity: |
1, This antibody reacts specifically with Kv1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
1, KLH conjugated synthetic peptide derived from human Kv1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Differences exist in the patterns of trafficking, Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), KV1, KV1, KV1, KV2, KV3, The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits, and expression patterns, and other excitable cells, and they vary in their gating and permeation properties, biosynthetic processing and surface expression of the major KV1 subunits (KV1, muscles, subcellular distribution, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels, which include the KV1, 1, 2, 4, 5 and KV1, 6) expressed in rat and human brain, Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Kv1, 1 RBK1 HUK1 MBK1 KCNA1 |
| Also known as: |
1 Polyclonal Antibody, Kv1 |
| Other name: |
1 Polyclonal, Anti-Kv1 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
1, Kv1 |
| Short name: |
1 (Polyclonal) Fluor 594, Anti-Kv1 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, 1 (polyclonal), antibody to-Kv1 |
| Alternative technique: |
polyclonals |
| Identity: |
305 |
| Gene: |
AEMK |
More about : AEMK |
| Long gene name: |
potassium voltage-gated channel subfamily A member 1 |
| Synonyms gene name: |
member 1 (episodic ataxia with myokymia) , potassium voltage-gated channel, shaker-related subfamily |
| Locus: |
12p13, 32 |
| Discovery year: |
1991-08-13 |
| GenBank acession: |
L02750 |
| Entrez gene record: |
3736 |
| Pubmed identfication: |
1349297 8821794 16382104 |
| RefSeq identity: |
NM_000217 |
| Classification: |
Potassium voltage-gated channels |
| Havana BLAST/BLAT: |
OTTHUMG00000044398 |