| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CTRP5 |
| Specificity: |
This antibody reacts specifically with CTRP5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CTRP5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A mutation within the C1q domain of CTRP5 results in abnormal high molecular weight aggregate formation, By forming an extracellular hexagonal lattice, CTRP5 (Complement C1q tumor necrosis factor-related protein 5) is a 243 amino acid secreted and membrane-associated protein that contains a collagen-like domain and a C1q domain, CTRP5 facilitates the adhesion of basal retinal pigment epithelium to Bruchâ, CTRP5 is a short-chain collagen that is expressed in retinal pigment epithelium as well as brain, This mutation may result in the presentation of late-onset retinal degeneration (LORD), an autosomal dominant disorder that is characterized by punctate yellow-white deposits in the retinal fundus and night blindness, liver and placenta, lung, the innermost layer of the choroid, which alters its structure and interactions, &euro, &trade, Members of the C1q superfamily have diverse functions that are related to cell adhesion and basement membrane components, s membrane |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CTRP5 DKFZp586B0621 LORD |
| Also known as: |
CTRP5 Polyclonal Antibody |
| Other name: |
Anti-CTRP5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CTRP5 |
| Short name: |
Anti-CTRP5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CTRP5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14344 |
| Gene: |
C1QTNF5 |
More about : C1QTNF5 |
| Long gene name: |
C1q and tumor necrosis factor related protein 5 |
| Synonyms name: |
complement-c1q tumor necrosis factor-related protein 5 myonectin |
| Locus: |
11q23, 3 |
| Discovery year: |
2001-10-02 |
| GenBank acession: |
AF329841 |
| Entrez gene record: |
114902 |
| Pubmed identfication: |
12944416 |
| RefSeq identity: |
NM_015645 |
| Classification: |
C1q and TNF related |
| Havana BLAST/BLAT: |
OTTHUMG00000166198 |