| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SSA reductase/AKR7A2 |
| Specificity: |
This antibody reacts specifically with SSA reductase/AKR7A2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AKR7A2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, More specifically, The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds, notably the liver, thus acting as an endogenous chemo-preventative agent, The aldo-keto reductase 7 (AKR7) family includes AKR7A2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AFAR |
| Also known as: |
SSA reductase/AKR7A2 Polyclonal Antibody |
| Other name: |
Anti-SSA reductase/AKR7A2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SSA reductase/AKR7A2 |
| Short name: |
Anti-SSA reductase/AKR7A2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SSA reductase/AKR7A2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
389 |
| Gene: |
AKR7A2 |
More about : AKR7A2 |
| Long gene name: |
aldo-keto reductase family 7 member A2 |
| Synonyms name: |
aflatoxin aldehyde reductase |
| Locus: |
1p36, 13 |
| Discovery year: |
1998-11-17 |
| GenBank acession: |
AF026947 |
| Entrez gene record: |
8574 |
| Pubmed identfication: |
9576847 |
| RefSeq identity: |
NM_003689 |
| Classification: |
Aldo-keto reductases |
| Havana BLAST/BLAT: |
OTTHUMG00000002522 |