| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SH3GL3 |
| Specificity: |
This antibody reacts specifically with SH3GL3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SH3GL3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Both Endophilin II and Endophilin III are detected in a variety of tissues, Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery, II and III, SH3P8 and SH3P13, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals, The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, These proteins associate with Amphiphysin, as Endophilin I is ex- pressed only in the brain, or alternatively known as SH3P4, respectively, The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SH3D2C SH3P13 CNSA3 EEN-B2 HsT19371 |
| Also known as: |
SH3GL3 Polyclonal Antibody |
| Other name: |
Anti-SH3GL3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SH3GL3 |
| Short name: |
Anti-SH3GL3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SH3-domain GRB2-like 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CNSA3 and EEN-B2 and HsT19371 and SH3D2C and SH3P13, Cytoplasm, SH3GL3 and IDBG-27199 and ENSG00000140600 and 6457, SH3GL3 and IDBG-630090 and ENSBTAG00000018004 and 520311, Sh3gl3 and IDBG-196717 and ENSMUSG00000030638 and 20408, identical protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0007417 and central nervous system development and biological process this GO :0008289 and lipid binding and molecular function this GO :0031901 and early endosome membrane and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008289 : lipid binding and also this GO :0042802 : identical protein binding, this GO :0008289 : lipid binding, this GO :0042802 : identical protein binding, SH3-domain GRB2-like 3 |
| Identity: |
10832 |
| Gene: |
SH3GL3 |
More about : SH3GL3 |
| Long gene name: |
SH3 domain containing GRB2 like 3, endophilin A3 |
| Synonyms gene name: |
SH3 domain containing GRB2 like 3 |
| Synonyms name: |
endophilin A3 |
| Locus: |
15q25, 2 |
| Discovery year: |
1996-10-26 |
| GenBank acession: |
AF036271 |
| Entrez gene record: |
6457 |
| Pubmed identfication: |
9169142 |
| RefSeq identity: |
NM_003027 |
| Classification: |
N-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000147361 |